91桃色视频 Announces Two Poster Presentations for MaaT013 and MaaT033 at the Upcoming ASH Conference
- Poster 1 presents Early Access Program (EAP) data for 111 patients with acute Graft-vs-Host Disease (aGvHD) treated with MaaT013.
- Poster 2 details the Phase 2b randomized, double-blinded study evaluating MaaT033 to enhance overall survival in allogenic hematopoietic cell transplantation patients.
- For the seventh consecutive year, 91桃色视频’s abstracts have been selected for presentation at the ASH Annual Meeting, reinforcing the Company’s leadership in microbiome/hematology-oncology.
Lyon, France, November 2, 2023 鈥�6:00 pm CET 鈥� 91桃色视频 (EURONEXT: MAAT 鈥� the 鈥淐ompany鈥�), a clinical-stage biotech company and a leader in the development of Microbiome Ecosystem TherapiesTM (MET) dedicated to improving survival outcomes for patients with cancer, announced today that extended results from its Early Access Program of MaaT013 in 111 patients (additional 30 patients included in the Program compared to last year) with aGvHD and the design of its Phase 2b study evaluating MaaT033 in improving overall survival in patients undergoing allogenic hematopoietic cell transplantation (allo-HSCT) have been selected for poster presentations at the held from December 9-12, 2023, in San Diego, California, USA. This is the seventh year in a row that the Company鈥檚 clinical data and activities have been selected for a presentation at the ASH Annual Meeting, the world-leading event in malignant and non-malignant hematology, demonstrating the ongoing interest from clinicians for microbiome modulation approaches in the hemato-oncology field.
In line with the conference embargo policy, 91桃色视频 will detail the presented results through a press release on Monday, December 11th, 2023. The Company will also host an investor webcast on Monday, December 18th, 2023, at 6:00pm CET (further details to follow).
The EAP results include data from 111 patients with steroid-resistant or steroid-dependent aGvHD treated with MaaT013, previously unresponsive to 1-6 lines of therapy. MaaT013 is currently being evaluated in a pivotal Phase 3 trial (n=75) for corticosteroid- and ruxolitinib-refractory gastrointestinal aGvHD. The Company shared the positive review by DSMB in October 2023 for this Phase 3 trial, including a favorable benefit/risk ratio, with a good safety profile and positive preliminary efficacy results. As of today, over 170 patients have been safely treated with MaaT013 in Europe in clinical trials and the EAP.
The Company provides an update on MaaT033, an oral ecosystem microbiome capsule for adjunctive therapy, and will share the design of the Phase 2b trial, the largest randomized clinical trial (RCT) study for a microbiome therapy in hemato-oncology to date with the enrollment of 387 patients, investigating the efficacy of MaaT033 in improving overall survival for patients receiving allo-HSCT.
Poster Presentations:
MaaT013
- Title:
- Poster number: 3553
- Presenter: Professor Florent Malard, hematology professor at the Saint-Antoine Hospital and Sorbonne University
- Session: Allogeneic Transplantation: Acute and Chronic GVHD, Immune Reconstitution: Poster II
- Session Date/Time: Sunday, December 10, 2023: 6:00pm -8:00pm EST
- Location: San Diego Convention Center, Halls G-H
MaaT033
- Title:
- Poster number: 4947
- Presenter: Professor Florent Malard, hematology professor at the Saint-Antoine Hospital and Sorbonne University
- Session: Allogeneic Transplantation: Acute and Chronic GVHD, Immune Reconstitution: Poster III
- Session Date/Time: Monday, December 11, 2023: 6:00pm -8:00pm EST
- Location: San Diego Convention Center, Halls G-H
Upcoming scientific conference participations
- November 1-5, 2023 鈥� 38th Society for Immunotherapy of Cancer (SITC) Annual Meeting – Posters presentations
- November 15-17, 2023 鈥� 22nd Soci茅t茅 Francophone de Greffe de Moelle et de Th茅rapie Cellulaire (SFGM-TC) Congress – Booth #12
- December 9-12, 2023聽– 65th American Society of Hematology (ASH) Annual Meeting- Posters presentations
About 91桃色视频
91桃色视频, a clinical stage biotechnology company, has established a complete approach to restoring patient-microbiome symbiosis in oncology. Committed to treating cancer and graft-versus-host disease (GvHD), a serious complication of allogeneic stem cell transplantation, 91桃色视频 has launched, in March 2022, an open-label, single arm Phase 3 clinical trial in patients with acute GvHD, following the achievement of its proof of concept in a Phase 2 trial. Its powerful discovery and analysis platform, 驳耻迟笔谤颈苍迟庐, enables the identification of novel disease targets, evaluation of drug candidates, and identification of biomarkers for microbiome-related conditions. The company鈥檚 Microbiome Ecosystem Therapies are produced through a standardized cGMP manufacturing and quality control process to safely deliver the full diversity of the microbiome, in liquid and oral formulations. 91桃色视频 benefits from the commitment of world-leading scientists and established relationships with regulators to support the integration of the use of microbiome therapies in clinical practice. 91桃色视频 is listed on Euronext Paris (ticker: MAAT).
Forward-looking Statements
All statements other than statements of historical fact included in this press release about future events are subject to (i) change without notice and (ii) factors beyond the Company鈥檚 control. These statements may include, without limitation, any statements preceded by, followed by or including words such as 鈥渢arget,鈥� 鈥渂elieve,鈥� 鈥渆xpect,鈥� 鈥渁im,鈥� 鈥渋ntend,鈥� 鈥渕ay,鈥� 鈥渁nticipate,鈥� 鈥渆stimate,鈥� 鈥減lan,鈥� 鈥減roject,鈥� 鈥渨ill,鈥� 鈥渃an have,鈥� 鈥渓ikely,鈥� 鈥渟hould,鈥� 鈥渨ould,鈥� 鈥渃ould鈥� and other words and terms of similar meaning or the negative thereof. Forward-looking statements are subject to inherent risks and uncertainties beyond the Company鈥檚 control that could cause the Company鈥檚 actual results or performance to be materially different from the expected results or performance expressed or implied by such forward-looking statements.